Effectiveness of Toothpaste Containing REFIX Technology against Dentin Hypersensitivity: A Randomized Clinical Study.

AIM: This clinical study aimed to evaluate the efficacy of a toothpaste containing a proprietary REFIX technology (Regenerador + Sensitive DentalClean, Rabbit Corp) against dentin hypersensitivity. MATERIALS AND METHODS: Fifty-three volunteers who fulfilled the inclusion criteria and signed the consent form were included. They were examined for dentin hypersensitivity. The participants received a 1-second blast of air, and the tooth sensitivity, from 0 to 10, was immediately evaluated using a visual analog scale (VAS). Then, the participants brushed their teeth with the multifunctional toothpaste, and dentin hypersensitivity was tested a second time using the same scale. The participants continued to use the toothpaste three times a day for 1 week, after which dentin hypersensitivity was recorded for the third time. Data were statistically analyzed using analysis of variance (ANOVA) and Tukey's test (α = 0.05). RESULTS: The mean patient age was 40 years, and 70% of the 53 subjects were female. There was a significant reduction in dentin hypersensitivity immediately after using the toothpaste and after 1 week. The baseline mean patient-reported pain score was severe (6.5 ± 2.4). Immediately after the first use of the toothpaste, the mean reported pain significantly decreased to mild pain (2.5 ± 2.5) (p < 0.05). After 1 week of consistent use of the toothpaste, the pain score reduced significantly (0.7 ± 1.2) (p < 0.05), and most participants reported no pain, demonstrating the effectiveness of the REFIX technology against dentin hypersensitivity. CONCLUSION: This clinical trial shows that the use of the phosphate-based desensitizing toothpaste containing REFIX technology significantly reduces dentin hypersensitivity after 1 week of consistent use. CLINICAL SIGNIFICANCE: The absence of pain, a desired clinical condition in patients with dentin hypersensitivity, was reached with the use of desensitizing toothpaste containing REFIX technology after 1 week of use. Such condition positively impacts quality of life, providing a healthier daily routine for patients.

Chlorhexidine use at dentistry

Diseases prevention and health promotion have been standing out in moderm dentistry. Biofilm control still is a major challenge to clinicians, independently of treatment that will be done. Success during and after treatment is related to professional care and to patient cooperation. Mechanic methods to maintenance of oral hygiene cannot be substituted, but , sometimes, it is difficult or even impossible to control biofilm suitably. At these cases, appropriated use of chemistry agents should be a good alternative as co adjuvant in different treatments. Chlorhexidine is the product that has been showing best clinics results at biofilm control when compared to others topical antimicrobial agents. Chlorhexidine has different applicability since it can be used as a surface and root canal disinfectant and effective antimicrobial at biofilm control, gingivitis and periodontal disease prevention and treatment, control of S. mutans colonization, caries prevention and prevention of possible systemic infection for bacteria that could occur after simple proceedings like suture removal. Chlorhexidine gluconate should be used for prevention or therapeutics at different presentations like solution, varnish, sub-gengival solution, intra oral gadgets, and others. Protocol of concentration and period of application vary according the use and it must be proposed according to individual needs of each patient